Cat Symptom Reference Guide

Cats are masters at hiding illness, making it crucial to recognize subtle signs of health problems. This guide helps you identify common symptoms, understand their potential causes, and know when to seek veterinary care.

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Emergency Symptoms — Seek Immediate Veterinary Care

Contact an emergency veterinarian immediately if your cat shows any of these signs:

  • Difficulty breathing, open-mouth breathing, or blue/gray gums
  • Straining to urinate (especially male cats) or crying in litter box
  • Complete inability to urinate for more than 12 hours
  • Collapse, unresponsiveness, or extreme weakness
  • Seizures
  • Severe trauma (hit by car, fall from height, animal attack)
  • Profuse bleeding that won't stop
  • Suspected poisoning
  • Paralysis or sudden inability to use back legs
  • Distended, hard, painful abdomen
  • Severe, persistent vomiting (especially with blood)

ASPCA Poison Control: (888) 426-4435

Digestive Symptoms

Vomiting

Occasional vomiting (once every few weeks) may be normal, but frequent vomiting warrants investigation.

Diarrhea

Constipation

Loss of Appetite

Hepatic Lipidosis Warning

When cats stop eating, their bodies mobilize fat for energy, which can overwhelm the liver and cause hepatic lipidosis (fatty liver disease). This is especially dangerous in overweight cats. If your cat hasn't eaten in 24-48 hours, contact your veterinarian immediately.

Urinary Symptoms

Increased Urination (Polyuria)

Straining to Urinate or Urinary Blockage

Blood in Urine (Hematuria)

Male Cat Urinary Emergency

Male cats can develop life-threatening urinary blockages due to their narrow urethra. If your male cat is straining to urinate, making frequent trips to the litter box, vocalizing in pain, or producing no urine, seek emergency veterinary care IMMEDIATELY. This condition can be fatal within 24-48 hours.

Respiratory Symptoms

Sneezing and Nasal Discharge

Coughing

Difficulty Breathing

Skin and Coat Symptoms

Excessive Scratching or Hair Loss

Lumps and Bumps

Wounds and Abscesses

Eye Symptoms

Eye Discharge

Squinting, Pawing at Eye, or Eye Held Closed

Cloudiness, Color Change, or Pupil Abnormality

Ear Symptoms

Head Shaking or Ear Scratching

Behavioral and Neurological Symptoms

Lethargy

Hiding

Increased Vocalization

Seizures

Loss of Balance or Coordination

Weight and Appetite Changes

Weight Loss

Increased Appetite with Weight Loss

Increased Thirst

Pain Indicators in Cats

Cats instinctively hide pain. Learn to recognize these subtle signs:

Behavioral Signs of Pain

Physical Signs of Pain

Sources and Further Reading

Describe Your Cat's Symptoms to Our AI

Not sure what your cat's symptoms mean? Our AI assistant can help you understand what might be happening and whether you need to see a vet urgently.

Sources & References

This guide references the following veterinary and scientific sources:

Content is periodically reviewed against current veterinary literature. Last reviewed: February 2026. For the most current medical guidance, consult your veterinarian directly.

Veterinary Guidance Notice

Consult your veterinarian for advice specific to your pet. While this guide references peer-reviewed veterinary sources and established breed health data, online health information has inherent limitations. Breed predispositions describe population-level trends — your individual pet may face different risks based on their genetics, environment, diet, and lifestyle. Use this resource as a starting point for informed conversations with your veterinary care team, not as a substitute for professional evaluation.

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